Nanomedicine: Nanotechnology, Biology and Medicine
Volume 1, Issue 1 , Pages 22-30, March 2005

Nanostructure-mediated drug delivery

Zyvex Corporation, Richardson, Texas

Received 21 October 2004; accepted 30 November 2004.

Abstract 

Nanotechnology is expected to have an impact on all industries including semiconductors, manufacturing, and biotechnology. Tools that provide the capability to characterize and manipulate materials at the nanoscale level further elucidate nanoscale phenomena and equip researchers and developers with the ability to fabricate novel materials and structures. One of the most promising societal impacts of nanotechnology is in the area of nanomedicine. Personalized health care, rational drug design, and targeted drug delivery are some of the benefits of a nanomedicine-based approach to therapy. This review will focus on the development of nanoscale drug delivery mechanisms. Nanostructured drug carriers allow for the delivery of not only small-molecule drugs but also the delivery of nucleic acids and proteins. Delivery of these molecules to specific areas within the body can be achieved, which will reduce systemic side effects and allow for more efficient use of the drug.

Key words: Drug delivery, Nanotechnology, Nanomedicine

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PII: S1549-9634(05)00012-2

doi:10.1016/j.nano.2004.11.009

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 1, Issue 1 , Pages 22-30, March 2005