« Previous
Next »
Nanomedicine: Nanotechnology, Biology and Medicine
Volume 2, Issue 2
, Pages 53-65
, June 2006
Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems
References
- PEGylated PLGA nanoparticles as protein carriers: synthesis, preparation and biodistribution in rats. J Contr Rel. 2001;71:203–211
- Binding and uptake of biodegradable poly-d,l-lactide micro- and nanoparticles in intestinal epithelia. Eur J Pharm Sci. 1998;6:153–163
- . Biodegradable polymeric nanoparticles as drug delivery devices. J Contr Rel. 2001;70:1–20
- . Current methods for attaching targeting ligands to liposomes and nanoparticles. J Pharm Sci. 2004;93:1980–1992
- . Oral absorption of peptides and proteins. S.T.P. Pharma Sci. 1992;2:301–312
- The challenge of proteolytic enzymes in intestinal peptide delivery. J Contr Rel. 1997;46:39–57
- . Peptide absorption and hydrolysis. In: Johnson LR editors. Physiology of the gastrointestinal tract. New York: Raven Press; 1981;p. 1073–1095
- . Proteases and proteolysis in the lysosome. Experientia. 1992;151–157
- . Bacterial glycosidase. In: Drasar BS, Hill MJ editor. Human intestinal flora. London: Academic Press; 1974;p. 54–71
- . Oral Contrled release technology for peptides: status and future prospects. Pharm Res. 1996;13:1760–1764
- . Overcoming enzymatic and absorption barriers to non-parenterally administered protein and peptide drugs. J Contr Rel. 1994;29:239–252
- . Mechanisms of absorption enhancement and tight junction regulation. J Contr Rel. 1994;29:253–267
- . Nano- and microparticles for the delivery of polypeptides and proteins. Adv Drug Del Rev. 1993;10:141–162
- . Oral route of peptide and protein drug delivery. In: Lee VHL editors. Protein and peptide drug delivery. New York: Marcel Dekker; 1991;p. 691–738
- . Liposome-entrapped calcitonin and parathyroid hormone are orally effective in rats. Horm Metab Res. 1991;23:166–167
- . Insulin in w/o/w multiple emulsions: preparation, characterization and determination of stability towards proteases in vitro. J Microencapsulation. 1997;14:311–319
- . Absorption of insulin using water-in-oil-in-water emulsion from enteral loop in rats. Biol Pharm Bull. 1995;18:1718–1723
- . Hypoglycemic effect of novel oral microspheres of insulin with protease inhibitor in normal and diabetic rats. Int J Pharm. 1992;78:9–16
- . Polymeric nano-microparticles for the oral delivery of peptides and peptidomimetics. Adv Drug Del Rev. 1998;34:171–189
- . Controlled drug delivery with nanoparticles: current possibilities and future trends. Eur J Pharm Biopharm. 1995;41:2–13
- . Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Del Rev. 2003;55:329–347
- . Nanoparticles. In: Mathiowitz E editors. Nanoparticles. New York: Wiley and Son, Inc; 1999;p. 641–664
- . Nanoparticle uptake by rat gastrointestinal mucosa: quantitation and particles size dependency. J Pharm Pharmacol. 1990;42:821–826
- . Controlled vaccine release in gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyer's patches. J Contr Rel. 1990;11:205–214
- . The effect of site of administration in the gastrointestinal tract on the absorption of insulin from nanocapsules in diabetic rats. J Pharm Pharmacol. 1991;43:1–5
- . Ileal uptake of polyalkylcyanoacrylate nanocapsules in the rat. J Pharm Pharmacol. 2000;52:1049–1056
- . Quantitative and microautoradiographic study on mouse intestinal distribution of polycyanoacrylate nanoparticles. Int J Pharm. 1989;55:39–45
- . Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small intestine. Biol Cell. 1987;61:69–76
- . Poly(alkylcyanoacrylates) as biodegradable materials for biomedical applications. Adv Drug Del Rev. 2003;55:519–548
- . The oral absorption of micro and nanoparticulates: neither exceptional nor unusual. Pharm Res. 1997;14:259–266
- . Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics. Adv Drug Del Rev. 2001;50:107–142
- . Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake?. Eur J Pharm Biopharm. 2000;50:147–160
- . Polyalkylcyanoacrylates as colloidal drug carriers. Crit Rev Ther Drug Carrier Syst. 1988;5:1–20
- . Drug-loaded nanoparticles—preparation methods and drug targeting issues. Eur J Pharm Biopharm. 1993;39:173–191
- . Characterization of poly (lactic-co-glycolic acid) based nanoparticulate system for enhanced delivery of antigens to dendritic cells. Vaccine. 2004;22:2406–2412
- . Oral and parenteral administration of insulin associated to hydrolyzable nanoparticles. Acta Pharm Technol. 1980;26:220–222
- . Nanoparticles as carriers for oral peptide absorption: studies on particle uptake and fate. J Contr Rel. 1995;36:39–46
- . Further histological evidence of the gastrointestinal absorption of polystyrene nanospheres in the rat. Int J Pharm. 1992;84:245–252
- . Nanosphere and microsphere uptake via Peyer's patches: observation on the rate of uptake in the rat after a single oral dose. Int J Pharm. 1992;86:239–246
- . Preparation of aqueous polymeric nanodispersions by a reversible salting-out process: influence of process parameters on particle size. Int J Pharm. 1992;87:247–253
- . The preparation and acute antihypertensive effects of a nanocapsular form of darodipine, a dihydropyridine calcium entry blocker. Pharm Res. 1991;8:734–738
- Poly(ɛ-caprolactone) nanospheres as an alternative way to reduce amphotericin B toxicity. Int J Pharm. 1997;158:19–27
- . Nanocapsule formation by interfacial deposition following solvent displacement. Int J Pharm. 1989;55:R1–R4
- . Jejunal absorption, pharmacological activity, and pharmacokinetic evaluation of indomethacin-loaded poly(d,l-lactide) and poly(isobutyl-cyanoacrylate) nanocapsules in rats. Pharm Res. 1991;8:101–105
- . Nanoparticles as carriers for growth hormone releasing factors (GRF). J Contr Rel. 1991;15:3–13
- . Encapsulation of insulin for oral administration preserves interaction of the hormone with its receptor in vitro. Diabetes. 1992;41:451–456
- . Nasal absorption of insulin in dogs. Diabetes. 1978;27:296–299
- . A new approach to the oral administration of insulin and other peptide drugs. Science. 1986;233:1081–1084
- . Oral delivery of insulin. Lancet. 1989;2:1518–1519
- . Oral administration of insulin by encapsulation within liposomes. FEBS Lett. 1976;62:60–63
- . New approach for oral administration of insulin with polyalkylcyanoacrylate nanocapsules as drug carrier. Diabetes. 1988;37:246–251
- . Study of the mechanism of insulin encapsulation in poly(isobutylcyanoacrylate) nanocapsules obtained by interfacial polymerization. J Biomed Mater Res. 1999;47:568–576
- Insulin-loaded nanocapsules for oral administration: in vitro and in vivo investigation. Drug Dev Res. 2000;49:109–117
- . Production and evaluation of orally administered insulin nanoparticles. Drug Dev Ind Pharm. 1982;8:531–546
- . Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions. Pharm Res. 2000;17:684–689
- . Development of a new process for the manufacture of polyisobutylcyanoacrylate nanocapsules. Int J Pharm. 1986;28:125–132
- . Nanocapsules as carriers for oral peptide delivery. J Contr Rel. 1990;13:233–239
- . Visualization of insulin-loaded nanocapsules: in vitro and in vivo studies after oral administration to rats. Pharm Res. 2003;207:1071–1084
- . Insulin nanocapsules: variations in the biological response depending on the administration site along the digestive tract. In: Whateley TL editors. Microencapsulation of drugs. Chur, Switzerland: Hardwood Academic Publishers; 1992;p. 233–242
- . Poly(alkylcyanoacrylate) nanocapsules as a delivery system in the rat for octreotide, a long-acting somatostatin analogue. J Pharm Pharmacol. 1997;49:949–954
- . Isobutylcyanoacrylate nanoparticles as drug carrier for oral administration of insulin. Proc Int Symp Contr Rel Bioact Mater. 1991;18:97–98
- . Novel oral microspheres of insulin with protease inhibitor protecting from enzymatic degradation. Int J Pharm. 1992;78:1–7
- Biologically erodable microspheres as potential oral drug delivery systems. Nature. 1997;386:410–414
- . In vitro release and oral bioactivity of insulin in diabetic rats using nanocapsules dispersed in biocompatible microemulsion. J Pharm Pharmacol. 2002;54:473–480
- . Production of insulin-loaded poly(ethylene glycol)/poly(l-lactide) (PEG/PLA) nanoparticles by gas antisolvent techniques. J Pharm Sci. 2001;90:1628–1636
- . Production of protein nanoparticles by electrospray drying. J Aerosol Sci. 1998;29:561–574
- Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int J Pharm. 2002;249:139–147
- . In vitro degradation of insulin-loaded poly(n-butylcyanoacrylate) nanoparticles. Biomaterials. 2004;25:4375–4382
- . Co-polymerized peptide particles (CPP) I: synthesis, characterization and in vitro studies on a novel oral nanoparticulate delivery system. J Contr Rel. 1996;41:271–281
- . Co-polymerized peptide particles II: oral uptake of a novel co-polymeric nanoparticulate delivery system for peptides. J Contr Rel. 1996;42:65–73
- . New surface-modified lipid nanoparticles as delivery vehicles for salmon calcitonin. Int J Pharm. 2005;296:122–132
- . Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics. Adv Drug Del Rev. 1998;34:171–189
- . Calcitonin and insulin in isobutylcyanoacrylate nanocapsules: protection against proteases and effect on intestinal absorption in rats. J Pharm Pharmacol. 1994;46:547–552
- . Mucoadhesive d,l-lactide/glycolide copolymer nanospheres coated with chitosan to improve oral delivery of calcitonin. Pharm Dev Technol. 2000;5:77–85
- Oral peptide delivery using nanoparticles composed of novel graft copolymers having hydrophobic backbone and hydrophilic branches. Int J Pharm. 1997;149:93–106
- . Application of central composite designs to the preparation of polycaprolactone nanoparticles by solvent displacement. J Pharm Sci. 1996;85:206–213
- . Targeting solid tumours: challenges, disappointments, and opportunities. Adv Drug Del Rev. 1995;17:117–127
- . Nanoparticulate controlled release system for cancer therapy. In: Wise DL editors. Handbook of pharmaceutical controlled release technology. New York: Marcel Dekker; 2000;p. 287–300
- . Distribution of polyhexylcyanoacrylate nanoparticles in nude mice bearing human osteosarcoma. J Pharm Sci. 1986;75:256–258
- . Pharmacokinetics and distribution of a biodegradable drug-carrier. Int J Pharm. 1983;15:335–345
- . Distribution of polyhexylcyanoacrylate nanoparticles in nude mice bearing human osteosarcoma. In: Rygaard JR, Brünner N, Graem N, Spang-Thomsen M editor. Immune-deficient animals in biomedical research. Basel: Karger; 1987;p. 401
- . Nanoparticulate systems for brain delivery of drugs. Adv Drug Del Rev. 2001;47:65–81
- . Double-coated poly(butylcynanoacrylate) nanoparticulate delivery systems for brain targeting of dalargin via oral administration. J Pharm Sci. 2005;94:1343–1353
- . Efficacy of oral dalargin-loaded nanoparticle delivery across the blood–brain barrier. Peptides. 1998;19:777–780
- . Immune mechanisms in enteric infections. In: Holmgren J, Linderberg A, Molby RE editor. Development of vaccines and drugs against diarrhea. Bromley, UK: Studenlitteratur; 1986;p. 9–22
- . Intestinal barriers to bacteria and their toxins. Annu Rev Med. 1988;41:393–400
- . Intestinal absorption of proteins and macromolecules and the immunological response. Crit Rev Ther Drug Carrier Syst. 1987;4:197–220
- . Oral vaccines: design and delivery. Int J Pharm. 1991;75:1–24
- . DNA vaccines: a review. J Intern Med. 2003;253:402–410
- . Formation of agglutinating and reagenic antibodies in rabbits following oral administration of soluble and particulate antigens. Int Arch Allergy Immunol Appl. 1969;35:579–590
- . Oral induction of the secretory antibody response by soluble and particulate antigens. Int Arch Allergy Immunol Appl. 1984;75:126–131
- . The role of Peyer's patches in intestinal humoral immune responses is limited to memory formation. Adv Exp Med Biol. 1987;216A:257–265
- . Polymerized micelles and their use as adjuvants in immunology. J Pharm Sci. 1976;65:1763–1766
- . The use of new polymethylmethacrylate adjuvants for split influenza vaccines. Exp Cell Biol. 1976;44:12–19
- . Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines. Pharm Res. 1997;14:1431–1436
- . Peptomer aluminum oxide nanoparticle conjugates as systemic and mucosal vaccine candidates: synthesis and characterization of a conjugate derived from the C4 domain of HIV-1MN gp 120. Bioconjug Chem. 1997;8:424–433
- . Polystyrene nanosphere and microsphere uptake and translocation via the gut mucosa after a single oral dose. J Pharm Pharmacol. 1991;43(Suppl):27
- . Anti-metastatic activity in vivo of MDP-L-alanyl-cholesterol (MTP-chol) entrapped in nanocapsules. Int J Immunopharmacol. 1991;13:167–173
- . Macrophage activation by a lipophilic derivative of muramyldipeptide within nanocapsules: investigation of the mechanism of drug delivery. J Nanoparticle Res. 1999;1:91–97
- . Chitosan-dextran sulfate nanoparticles for delivery of an anti-angiogenesis peptide. Lett Peptide Sci. 2003;10:621–629
- . Biodegradable nanoparticles for subcutaneous administration of growth hormone releasing factor (hGRF). J Contr Rel. 1992;20:67–78
- . Développment d'un injectable de testostérone à action prolongée à base de latex biodégradable. Proc III Congr Hispano-français Biopharm Pharmacocin. 1979;173–179
- . Cyclosporine A delivery to the eye: a pharmaceutical challenge. Eur J Pharm Biopharm. 2003;56:307–318
- . Development and evaluation of a prolonged acting drug delivery system for the treatment of glaucoma. In: Rubinstein MHE editors. Proceedings of the International Symposium of the British Pharmaceutical Technology Conference—Solid Dosage Research Unit. Liverpool. 1980;
- Polyester nanocapsules as new topical ocular delivery systems for cyclosporin A. Pharm Res. 1996;13:311–315
- . Studies on the transport pathway of PBCA nanoparticles in ocular tissues. J Microencapsulation. 1991;8:497–504
- Effect of cyclosporine A formulations on bovine corneal absorption: ex-vivo study. J Microencapsulation. 1997;14:457–467
- . Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A. Int J Pharm. 2001;224:159–168
- . Chitosan nanoparticles as new ocular drug delivery systems: in vitro stability, in vivo fate, and cellular toxicity. Pharm Res. 2004;21:803–810
- . Ocular drug delivery of progesterone using nanoparticles. J Microencapsulation. 1986;3:213–218
- . Distribution of poly-hexyl-2-cyano [3-14C]acrylate nanoparticles in healthy and chronically inflamed rabbit eyes. Int J Pharm. 1989;54:149–153
- Comparison of different models for the testing of pilocarpine eyedrops using conventional eyedrops and a novel depot formulation (nanoparticles). Graefes Arch Clin Exp Ophthalmol. 1989;227:188–193
- Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features. J Contr Rel. 2003;86:131–144
- . Nebulization of fluids of different physicochemical properties with air-jet and ultrasonic nebulizers. Pharm Res. 1995;12:1682–1688
- . Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy. Eur J Pharm Biopharm. 2004;57:1–8
- . Nebulizers for the generation of liposomal aerosols. Int J Pharm. 1998;173:117–152
- . The stability of liposomes to ultrasonic nebulization. Int J Pharm. 1996;145:95–102
- . Topical delivery of liposomally encapsulated interferon evaluated in a cutaneous herpes guinea-pig model. Antimicrob Agents Chemother. 1989;33:1217–1221
- . Transdermal delivery of minoxidil with block copolymer nanoparticles. J Contr Rel. 2004;97:477–484
- . Enhancement of nasal absorption of insulin using chitosan nanoparticles. Pharm Res. 1999;16:1576–1581
- Nasal delivery of insulin using novel chitosan based formulations: a comparative study in two animal models between simple chitosan formulations and chitosan nanoparticles. Pharm Res. 2002;19:998–1008
- . Intranasal administration of plasmid DNA-coated nanoparticles results in enhanced immune responses. J Pharm Pharmacol. 2002;54:1195–1203
- . Stealth PLA-PEG nanoparticles as protein carriers for nasal administration. Pharm Res. 1998;15:270–275
- . Caracterização e estabilidade fîsico-quimica de sistemas poliméricos nanoparticulados para administração de fármacos. Química Nova. 2003;26:726–737
- . Peroral drug delivery systems for peptides and proteins. S.T.P. Pharma Sci. 2002;12:213–221
- Controlled liberation of active principles by means of new galenic formulations. Rev Med Univ Navarra. 2001;45:19–34
- . Reversion of multidrug resistance by co-encapsulation of doxorubicin and cyclosporin A in polyalkylcyanoacrylate nanoparticles. Biomaterials. 2000;21:1–7
- Augmentation of transvascular transport of macromolecules and nanoparticles in tumours using vascular endothelial growth factor. Cancer Res. 1999;59:4129–4135
- . Polymeric nanoparticles as delivery system for influenza virus glycoproteins. J Contr Rel. 1998;54:15–27
- A novel hydrophobized polysaccharide/oncoprotein complex vaccine induces in vitro and in vivo cellular and humoral immune responses against HER2-expressing murine sarcomas. Cancer Res. 1998;58:3385–3390
- . Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract. Adv Drug Del Rev. 1998;34:191–219
- Magnetic resonance contrast enhancement of neovasculture with α(v)-β-(3)-targeted nanoparticles. Magn Reson Med. 2000;44:433–439
- . A novel and robust homogeneous fluorescence-based assay using nanoparticles for pharmaceutical screening and diagnostics. J Biomol Screen. 2000;5:227–238
- . Immunomagnetic concentration of antigens and detection based on scanning force microscopic immunoassay. J Immunol Methods. 1999;224:77–87
- Gene transfer by DNA-gelatin nanospheres. Arch Biochem Biophys. 1999;361:47–56
No financial conflict of interest was reported by the authors of this paper.
PII: S1549-9634(06)00049-9
doi: 10.1016/j.nano.2006.04.009
© 2006 Elsevier Inc. All rights reserved.
« Previous
Next »
Nanomedicine: Nanotechnology, Biology and Medicine
Volume 2, Issue 2
, Pages 53-65
, June 2006
