Nanomedicine: Nanotechnology, Biology and Medicine
Volume 3, Issue 1 , Pages 63-74 , March 2007

Hollow chitosan-alginate multilayer microcapsules as drug delivery vehicle: doxorubicin loading and in vitro and in vivo studies

  • Qinghe Zhao, PhD

      Affiliations

    • Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China
    • Key Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Hangzhou, China
  • ,
  • Baosan Han, PhD

      Affiliations

    • Center of the Organ Transplantation and Institute of Digestive Surgery, Ruijin Hospital, Medical College of Shanghai Jiaotong University, Shanghai, China
  • ,
  • Zhaohai Wang, MS

      Affiliations

    • Center of the Organ Transplantation and Institute of Digestive Surgery, Ruijin Hospital, Medical College of Shanghai Jiaotong University, Shanghai, China
  • ,
  • Changyou Gao, PhD

      Affiliations

    • Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China
    • Key Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Hangzhou, China
    • Corresponding Author InformationCorresponding author. Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China.
  • ,
  • Chenghong Peng, PhD

      Affiliations

    • Key Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Hangzhou, China
    • Center of the Organ Transplantation and Institute of Digestive Surgery, Ruijin Hospital, Medical College of Shanghai Jiaotong University, Shanghai, China
  • ,
  • Jiacong Shen

      Affiliations

    • Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China

Received 13 August 2006 ,Accepted 21 November 2006.

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 No conflict of interest was reported by the authors of this paper.

PII: S1549-9634(06)00341-8

doi: 10.1016/j.nano.2006.11.007

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 3, Issue 1 , Pages 63-74 , March 2007