Nanomedicine: Nanotechnology, Biology and Medicine
Volume 3, Issue 1 , Pages 86-88, March 2007

Preparation of ultrafine particles of azithromycin by sonochemical method

  • Zhen-bang Pi, PhD

      Affiliations

    • Faculty of Material Science and Chemistry Engineering, China University of Geosciences, Wuhan, P.R. China
    • Corresponding Author InformationCorresponding author. Faculty of Material Science and Chemistry Engineering, China University of Geosciences, Wuhan, 430074, P.R. China
  • ,
  • Xiao-yu Zhao, MS

      Affiliations

    • Institute of Solid State Physics, Chinese Academy of Sciences, HeFei, P.R. China
  • ,
  • Chao Yang, MS

      Affiliations

    • Institute of Solid State Physics, Chinese Academy of Sciences, HeFei, P.R. China
  • ,
  • Jin-bo Fei, MS

      Affiliations

    • Institute of Solid State Physics, Chinese Academy of Sciences, HeFei, P.R. China
  • ,
  • Xi-ke Tian, PhD

      Affiliations

    • Faculty of Material Science and Chemistry Engineering, China University of Geosciences, Wuhan, P.R. China
    • Institute of Solid State Physics, Chinese Academy of Sciences, HeFei, P.R. China

Received 20 January 2006; accepted 21 November 2006.

Abstract 

Sonochemical method was used to prepare ultrafine Azithromycin. The morphology and size distribution of the particles prepared were characterized by scanning electron micrograph (SEM) and Zetasizer Nanoinstrument. The chemical bonding of production was examined by Fourier transform infra-red absorption spectroscopy (FT-IR). The result shows that different diameter particles of Azithromycin were prepared, and no fundamental bonding change in the Azithromycin molecule after preparation.

Key words: Ultrafine particles, Azithromycin, Sonochemical method

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 No conflict of interest was reported by the authors of this paper.

PII: S1549-9634(06)00344-3

doi:10.1016/j.nano.2006.11.009

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 3, Issue 1 , Pages 86-88, March 2007