Original ArticleExperimentalAntimicrobial effects of silver nanoparticles
Section snippets
Preparation of Ag nanoparticles
Ag nanoparticles were made according to the recipe described in the literature [8], [9]. Briefly, a 100-mL aqueous solution of 1.0 × 10–3 M silver nitrate was mixed with a 300-mL aqueous solution of 2.0 × 10-3 M sodium borohydride. Triply distilled water was used for solutions, and both solutions were chilled to ice temperature before mixing. By mixing both solutions, Ag ions were reduced and clustered together to form monodispersed nanoparticles as a transparent sol in aqueous medium. The Ag
Characterization of the synthesized Ag nanoparticles
The prepared aqueous solution of Ag nanoparticles showed an absorption band at 391 nm as shown in Figure 1, which is a typical absorption band of spherical Ag nanoparticles due to their surface plasmon [8]. The stability of the concentrated solution was checked by observing its absorption spectrum after rediluting 10 times. The absorption spectrum of the rediluted solution depicts almost identical spectral features to the spectrum of the original solution of Ag nanoparticles (Figure 1, A). This
Discussion
It is well known that Ag ions and Ag-based compounds have strong antimicrobial effects [12], and many investigators are interested in using other inorganic nanoparticles as antibacterial agents [4], [12], [13], [14]. These inorganic nanoparticles have a distinct advantage over conventional chemical antimicrobial agents. The most important problem caused by the chemical antimicrobial agents is multidrug resistance. Generally, the antimicrobial mechanism of chemical agents depends on the specific
Acknowledgments
This work was supported by the NSI-NCRC program of KOSEF. D.H.J. was supported by BK21 program. H.J.L. was supported by the the Korean Research Foundation Grant funded by the Korea Government (MOEHRD) (R05-2004-10627-0).
References (21)
- et al.
Investigation of jumbo squid (Dosidicus gigas) skin gelatin peptides for their in vitro antioxidant effects
Life Sci
(2005) - et al.
Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidasole ligands
Polyhedron
(2004) - et al.
Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria
J Colloid Interface Sci
(2004) - et al.
Complex formation in solutions for chemical synthesis of nanoscaled particles prepared by borohydride reduction process
Nanostruct Mater
(1999) - et al.
Conduction electron spin resonance of small silver particles
Spectrochimaca Acta Part A
(2006) - et al.
Controlling wound bioburden with a novel silver-containing Hydrofiber dressing
Wound Repair Regen
(2004) - et al.
Bacterial heavy metal resistance: new surprises
Annu Rev Microbiol
(1996) - et al.
Antibacterial and bioactive silver-containing Na2O × CaO × 2SiO2 glass prepared by sol-gel method
J Mater Sci Mater Med
(2004) - et al.
The efficacy of silver-ion implanted catheters in reducing peritoneal dialysis-related infections
Perit Dial Int
(2003) - et al.
Multiple parameters for the comprehensive evaluation of the susceptibility of Escherichia coli to the silver ion
Biometals
(1998)
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No conflict of interest was reported by the authors of this paper.
J.S. Kim and E. Kuk contributed equally to this work.