Nanomedicine: Nanotechnology, Biology and Medicine
Volume 3, Issue 3 , Pages 173-183, September 2007

Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides

  • Noha Nafee, PharmD

      Affiliations

    • Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany
    • Faculty of Pharmacy, Department of Pharmaceutics, University of Alexandria, Alexandria, Egypt
  • ,
  • Sebastian Taetz, PharmD

      Affiliations

    • Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany
  • ,
  • Marc Schneider, PhD

      Affiliations

    • Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany
    • Corresponding Author InformationCorresponding author. Biopharmaceutics and Pharmaceutical Technology, Saarland University, Campus Saarbruücken, Bldg. A41, P.O. Box 151150, 66041 Saarbrücken, Germany
  • ,
  • Ulrich F. Schaefer, PhD

      Affiliations

    • Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany
  • ,
  • Claus-Michael Lehr, PhD

      Affiliations

    • Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany

Received 22 January 2007; accepted 15 March 2007. published online 10 August 2007.

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 No conflict of interest was reported by the authors of this paper.

PII: S1549-9634(07)00089-5

doi:10.1016/j.nano.2007.03.006

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 3, Issue 3 , Pages 173-183, September 2007