Nanomedicine: Nanotechnology, Biology and Medicine
Volume 4, Issue 3 , Pages 215-225 , September 2008

High-efficiency DNA injection into a single human mesenchymal stem cell using a nanoneedle and atomic force microscopy

  • Sung-Woong Han, PhD

      Affiliations

    • Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan
    • Department of Chemistry and Biotechnology, The University of Tokyo, Tokyo, Japan
    • ,
  • Chikashi Nakamura, PhD

      Affiliations

    • Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan
    • Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan
    • Corresponding Author InformationCorresponding author. Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan.
    • ,
  • Noriko Kotobuki, PhD

      Affiliations

    • Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan
    • ,
  • Ikuo Obataya, PhD

      Affiliations

    • Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan
    • ,
  • Hajime Ohgushi, PhD

      Affiliations

    • Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan
    • ,
  • Teruyuki Nagamune, PhD

      Affiliations

    • Department of Chemistry and Biotechnology, The University of Tokyo, Tokyo, Japan
    • ,
  • Jun Miyake, PhD

      Affiliations

    • Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan
    • Department of Chemistry and Biotechnology, The University of Tokyo, Tokyo, Japan
    • Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan

Received 10 December 2007 ,Accepted 5 March 2008.

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 The authors thank the Industrial Technology Research Grant Program in 2005 from the New Energy and Industrial Technology Development Organization of Japan. Sung-Woong Han acknowledges a postdoctoral fellowship for foreign researchers from the Japan Society for the Promotion of Science.

PII: S1549-9634(08)00039-7

doi: 10.1016/j.nano.2008.03.005

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 4, Issue 3 , Pages 215-225 , September 2008

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