Nanomedicine: Nanotechnology, Biology and Medicine
Volume 4, Issue 4 , Pages 273-282, December 2008

Emerging nanopharmaceuticals

The Pharmaceutical Research Institute at Albany College of Pharmacy, Rensselaer, New York, USA

Received 2 January 2008; accepted 3 June 2008. published online 22 July 2008.

Abstract 

A budding interest in nanopharmaceuticals has generated a number of advancements throughout recent years with a focus on engineering novel applications. Nanotechnology also offers the ability to detect diseases at much earlier stages, such as finding hidden or overt metastatic colonies often seen in patients diagnosed with breast, lung, colon, prostate, and ovarian cancer. Diagnostic applications could build upon conventional procedures using nanoparticles, such as colloidal gold, iron oxide crystals, and quantum dots. Additionally, diseases may be managed by multifunctional agents encompassing both imaging and therapeutic capabilities, thus allowing simultaneous monitoring and treatment. A detailed evaluation of each formulation is essential to expand our current nanopharmaceutical repertoire. However, the safety and long-term effects of nanoformulations must not be overlooked. This review will provide a brief discussion of the major nanopharmaceutical formulations as well as the impact of nanotechnology into the future.

Key words: Nanoparticles, Micelles, Dendrimers, Liposomes, Quantum dots

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 No conflict of interest was reported by the authors of this article.

PII: S1549-9634(08)00084-1

doi:10.1016/j.nano.2008.06.002

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 4, Issue 4 , Pages 273-282, December 2008