Nanomedicine: Nanotechnology, Biology and Medicine
Volume 4, Issue 4 , Pages 340-349 , December 2008

Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium

  • Tarl W. Prow, PhD

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
  • ,
  • Imran Bhutto, MD, PhD

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
  • ,
  • Sahng Y. Kim, MD

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
  • ,
  • Rhonda Grebe, BS

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
  • ,
  • Carol Merges, MS

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
  • ,
  • D. Scott McLeod

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
  • ,
  • Koichi Uno, MD, PhD

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
  • ,
  • Mohamed Mennon, MD

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
  • ,
  • Li Rodriguez, PhD

      Affiliations

    • Food and Drug Administration, Rockville, Maryland
  • ,
  • Kam Leong, PhD

      Affiliations

    • Duke University, Durham, North Carolina, USA
  • ,
  • Gerard A. Lutty, PhD

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland
    • Corresponding Author InformationCorresponding author. Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287-9115, USA.

Received 3 August 2007 ,Revised 19 February 2008 ,Accepted 6 June 2008.

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 This work was supported by the National Eye Institute grant R03EY013744 (G.L.), R01EY09357 (G.L.), EY01765 (Wilmer), the Johns Hopkins Hematology Training grant T32HL007525 (T.P.), the Altsheler Durell Foundation (G.L.), and unrestricted funds from a Research to Prevent Blindness grant (Wilmer).

PII: S1549-9634(08)00086-5

doi: 10.1016/j.nano.2008.06.003

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 4, Issue 4 , Pages 340-349 , December 2008