Nanomedicine: Nanotechnology, Biology and Medicine
Volume 5, Issue 1 , Pages 30-41 , March 2009

Endothelial permeability is controlled by spatially defined cytoskeletal mechanics: Atomic force microscopy force mapping of pulmonary endothelial monolayer

  • Anna A. Birukova, MD

      Affiliations

    • Division of Biomedical Sciences, Department of Medicine, Section of Pulmonary and Critical Care Medicine University of Chicago, Chicago, Illinois, USA
    • These authors contributed equally in this study.
  • ,
  • Fernando T. Arce, PhD

      Affiliations

    • Division of Biomedical Sciences, Department of Medicine, Section of Pulmonary and Critical Care Medicine University of Chicago, Chicago, Illinois, USA
    • Department of Medicine, Center for Nanomedicine, University of Chicago, Chicago, Illinois, USA
    • These authors contributed equally in this study.
  • ,
  • Nurgul Moldobaeva, BS

      Affiliations

    • Division of Biomedical Sciences, Department of Medicine, Section of Pulmonary and Critical Care Medicine University of Chicago, Chicago, Illinois, USA
  • ,
  • Steven M. Dudek, MD

      Affiliations

    • Division of Biomedical Sciences, Department of Medicine, Section of Pulmonary and Critical Care Medicine University of Chicago, Chicago, Illinois, USA
  • ,
  • Joe G.N. Garcia, MD

      Affiliations

    • Division of Biomedical Sciences, Department of Medicine, Section of Pulmonary and Critical Care Medicine University of Chicago, Chicago, Illinois, USA
  • ,
  • Ratnesh Lal, PhD

      Affiliations

    • Division of Biomedical Sciences, Department of Medicine, Section of Pulmonary and Critical Care Medicine University of Chicago, Chicago, Illinois, USA
    • Department of Medicine, Center for Nanomedicine, University of Chicago, Chicago, Illinois, USA
  • ,
  • Konstantin G. Birukov, MD, PhD

      Affiliations

    • Division of Biomedical Sciences, Department of Medicine, Section of Pulmonary and Critical Care Medicine University of Chicago, Chicago, Illinois, USA
    • Corresponding Author InformationCorresponding author. Division of Biomedical Sciences, Department of Medicine, Section of Pulmonary and Critical Medicine, University of Chicago, Chicago, IL 60637, USA.

Received 2 January 2008 ,Accepted 30 July 2008.

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 This work was supported by National Heart, Lung, and Blood Institutes grants HL076259, HL075349, and HL58064, the American Lung Association Career Investigator Grant (K.G.B.); National Scientist Developing Grant from the American Heart Association (A.A.B.), the American Lung Association Biomedical Research Grant (A.A.B.); and Department of Medicine Developmental Fund (R.L., F.T.A.).

PII: S1549-9634(08)00117-2

doi: 10.1016/j.nano.2008.07.002

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 5, Issue 1 , Pages 30-41 , March 2009