Nanomedicine: Nanotechnology, Biology and Medicine
Volume 5, Issue 4 , Pages 419-423, December 2009

A randomized multicenter phase II clinical trial of mitoxantrone-loaded nanoparticles in the treatment of 108 patients with unresected hepatocellular carcinoma

  • Qinghua Zhou, PhD

      Affiliations

    • Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy,Sichuan University, Chengdu, China
    • West China Hospital, Sichuan University, Chengdu, China
    • These authors contributed equally to this work.
  • ,
  • Xun Sun, PhD

      Affiliations

    • Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy,Sichuan University, Chengdu, China
    • These authors contributed equally to this work.
  • ,
  • Lingyuan Zeng, BS

      Affiliations

    • Sichuan Provincial Cancer Hospital, Chengdu, China
  • ,
  • Jie Liu, PhD

      Affiliations

    • Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy,Sichuan University, Chengdu, China
  • ,
  • Zhirong Zhang, PhD

      Affiliations

    • Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy,Sichuan University, Chengdu, China
    • Corresponding Author InformationCorresponding author. Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, China.

Received 31 October 2008; accepted 16 January 2009. published online 17 February 2009.

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 This work was supported by a grant from the National High Research and Development Program of China (863 program) (Grant 2007AA021800).

PII: S1549-9634(09)00047-1

doi:10.1016/j.nano.2009.01.009

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 5, Issue 4 , Pages 419-423, December 2009