Nanomedicine: Nanotechnology, Biology and Medicine
Volume 5, Issue 4 , Pages 419-423 , December 2009

A randomized multicenter phase II clinical trial of mitoxantrone-loaded nanoparticles in the treatment of 108 patients with unresected hepatocellular carcinoma

  • Qinghua Zhou, PhD

      Affiliations

    • Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy,Sichuan University, Chengdu, China
    • West China Hospital, Sichuan University, Chengdu, China
    • These authors contributed equally to this work.
  • ,
  • Xun Sun, PhD

      Affiliations

    • Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy,Sichuan University, Chengdu, China
    • These authors contributed equally to this work.
  • ,
  • Lingyuan Zeng, BS

      Affiliations

    • Sichuan Provincial Cancer Hospital, Chengdu, China
  • ,
  • Jie Liu, PhD

      Affiliations

    • Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy,Sichuan University, Chengdu, China
  • ,
  • Zhirong Zhang, PhD

      Affiliations

    • Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy,Sichuan University, Chengdu, China
    • Corresponding Author InformationCorresponding author. Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, China.

Received 31 October 2008 ,Accepted 16 January 2009.

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 This work was supported by a grant from the National High Research and Development Program of China (863 program) (Grant 2007AA021800).

PII: S1549-9634(09)00047-1

doi: 10.1016/j.nano.2009.01.009

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 5, Issue 4 , Pages 419-423 , December 2009