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Nanomedicine: Nanotechnology, Biology and Medicine
Volume 5, Issue 4
, Pages 410-418
, December 2009
PEGylated PLGA nanoparticles for the improved delivery of doxorubicin
References
- . Biodegradable polymeric nanoparticles as drug delivery devices. J Control Release. 2001;70:1–20
- . Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev. 1997;28:5–24
- . Biodegradable microspheres in drug-delivery. Crit Rev Ther Drug Carrier Syst. 1995;12:1–99
- . Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump. Clin Cancer Res. 2000;6:1949–1957
- . Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog Lipid Res. 2003;42:463–478
- . Ligand-specific targeting of microspheres to phagocytes by surface modification with poly(l-lysine)-grafted poly(ethylene glycol) conjugate. Pharm Res. 2003;20:237–246
- ‘Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption. Colloids Surfaces B–Biointerfaces. 2000;18:301–313
- PEGylated PLGA nanoparticles as protein carriers: synthesis, preparation and biodistribution in rats. J Control Release. 2001;71:203–211
- Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management. Circulation. 2004;109:3122–3131
- . Advantages of liposomal delivery systems for anthracyclines. Semin Oncol. 2004;31:5–15
- . Models for lymphoma. In: Coico R editors. Current protocols in immunology. Hoboken, NJ: John Wiley and Sons, Inc.; 2001;p. 20.6.1–20.6.30
- . Surface modification of biodegradable polyesters with fatty acid conjugates for improved drug targeting. Biomaterials. 2005;26:5727–5736
- . Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response. Science. 1977;197:165–167
- . Suppression of cardiotoxicity by overexpression of catalase in the heart of transgenic mice. J Biol Chem. 1996;271:12610–12616
- . Progressive cardiac dysfunction in adriamycin-induced cardiomyopathy rats. Eur J Heart Fail. 2000;2:373–378
- Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age. Proc Natl Acad Sci U S A. 2003;100:12929–12934
- . Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov. 2008;7:771–782
- . Doxorubicin pharmacokinetics after intravenous and intraperitoneal administration in the nude-mouse. Cancer Chemother Pharmacol. 1981;5:267–270
- . Anthracycline antitumour agents. Pharm World Sci. 1986;8:109–133
- . Anti-CD19-targeted liposomal doxorubicin improves the therapeutic efficacy in murine B-cell lymphoma and ameliorates the toxicity of liposomes with varying drug release rates. Clin Cancer Res. 2005;11:3567–3573
- Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles. Immunology. 2006;117:78–88
- . Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glyco-protein inhibition. J Control Release. 2006;112:208–213
- . Ability of doxorubicin-loaded nanoparticles to overcome multidrug resistance of tumor cells after their capture by macrophages. Pharm Res. 1999;16:1710–1716
- . Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new Polymer-Lipid Hybrid Nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer. J Control Release. 2006;116:275–284
This work was supported by a grant to W.M.S. from the National Institutes of Health (EB000487) and a career award to T.M.F. from the Wallace Coulter Foundation.
PII: S1549-9634(09)00056-2
doi: 10.1016/j.nano.2009.02.002
© 2009 Elsevier Inc. All rights reserved.
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Nanomedicine: Nanotechnology, Biology and Medicine
Volume 5, Issue 4
, Pages 410-418
, December 2009
