Nanomedicine: Nanotechnology, Biology and Medicine
Volume 6, Issue 3 , Pages 453-462 , June 2010

Release dynamics of ciprofloxacin from swellable nanocarriers of poly(2-hydroxyethyl methacrylate): an in vitro study

  • Raje Chouhan, MSc
    • ,
  • Anil K. Bajpai, PhD

      Affiliations

    • Corresponding Author InformationCorresponding author: Bose Memorial Research Laboratory, Department of Chemistry, Government Autonomous Science College, Jabalpur (MP) 482001, India.

Received 9 July 2009 ,Accepted 18 November 2009.

References 

  1. Mishra B, Patel BB, Tiwari S. Colloidal nanocarriers: a review on formulation technology, types and applications toward targeted drug delivery. Nanomedicine: Nanomed Biol Med. 2010;6:9–24
  2. Couvreur P, Vauthier C. Nanotechnology: intelligent design to treat complex disease. Pharm Res. 2006;23:1417–1450
  3. Parashar UK, Saxena PS. Srivastava Anchal. Role of nanomaterials in biotechnology. Digest J Nanomater Biostruct. 2008;3:81–87
  4. Lee HD, Kang Joong IK. Drug delivery system using biodegradable nanoparticles. Kona. 2006;24:159–166
  5. Kaparissides C, Alexandridou S, Kotti K, Chaitidou S. Recent advances in novel drug delivery systems. 2006;2: pp. 1-11. doi:10.2240/azonano0111.
  6. Wang AZ, Gu F, Zhang L, Chan JM, Radovic-Moreno A, Farokhzad OC, et al. Biofunctionalized targeted nanoparticles for therapeutic applications. Expert Opin Biol Ther. 2008;8:1063–1070
  7. Bhavane R, Karathanasis E, Annapragada AV. Triggered release of ciprofloxacin from nanostructured agglomerated vesicles. Int J Nanomed. 2007;2:407–418
  8. Rosemary MJ, MacLaren I, Pradeep T. Investigations of the antibacterial properties of ciprofloxacin@SiO2. Langmuir. 2006;22:10125–10129
  9. Tamayo M, Santiso R, Gosalvez J, Bou G, Fernandez JL. Rapid assessment of the effect of ciprofloxacin on chromosomal DNA from Escherichia coli using an in situ DNA fragmentation assay. BMC Microbiol. 2009;9:69–80
  10. Marzo A, Bal Do. Liquid chromatography as an analytical tool for selected antibiotic classes: a reappraisal addressed to pharmacokinetic applications. J Chromatogr A. 2002;B12:17–34
  11. Bajpai AK. Adsorption of a blood protein on to hydrophilic sponges based on poly(2-hydroxyethyl methacrylate). J Mater Sci Mater Med. 2004;15:583–592
  12. Kaparissides C, Alexandridou S, Kammona O, Dini E. Polymeric nano- and microparticles for controlled release applications. In: Workshop of CPERI. Department of Chemical Engineering and Chemical Process Engineering Research Institute, Aristotle University of Thessaloniki, Thessaloniki, Greece.. 2002;
  13. Tandon V , Bhagavatula SK, Nelson WC, Kirby BJ. Zeta potential and electroosmotic mobility in microfluidic devices fabricated from hydrophobic polymers: 1. The origins of charge. Electrophoresis. 2008;29:1092–1101
  14. Jahanshahi M, Babaei Z. Protein nanoparticle: a unique system as drug delivery vehicles. Afr J Biotech. 2008;7:4926–4934
  15. Kumari K, Kundu PP. Studies on in vitro release of CPM from semi-interpenetrating polymer network (IPN) composed of chitosan and glutamic acid. Bull Mater Sci. 2008;31:159–167
  16. Bundela H, Bajpai AK. Designing of hydroxyapatite-gelatin based porous matrix as bone substitute: correlation with biocompatibility aspects. Express Polym Lett. 2008;2:201–213
  17. Vanneaux V, Proust V, Cheron M, Madeleine , Odile Corriol , Francois Gimenez , et al. A physical and chemical stability study of amphotericin B lipid complexes (Abelcet) Besnard after dilution in dextrose 5%. EJHP-S. 2007;13:10–13
  18. Zhang L, Kosaraju SL. Biopolymeric delivery system for controlled release of polyphenolic antioxidants. Eur Polym J. 2007;43:2956–2966
  19. Li-Fang F, Wei He, Yong-Zhene C, Bai X, Qing Du, De-Ying C, et al. Studies of chitosan/Kollicoat SR 30D film-coated tablets for colonic drug delivery. Int J Pharm. 2009;375:8–15
  20. Prado HJ, Matulewicz MC, Bonelli PR, Cukierman AL. Preparation and characterization of a novel starch-based interpolyelectrolyte complex as matrix for controlled drug release. Carbohydrate Res. 2009;344:1325–1331
  21. Mc Gann MJ, Higginbotham CL, Geever LM, Nugent MJD. The synthesis of novel pH-sensitive poly(vinyl alcohol) composite hydrogels using a freeze/thaw process for biomedical applications. Int J Pharm. 2009;372:154–161
  22. Mahkam M, Mohammadia R, Siadat SOR. Synthesis and evaluation of biocompatible pH-sensitive hydrogels as colon-specific drug delivery systems. J Chin Chem Soc. 2006;53:727–733
  23. Jahanshahi M. Molecular nanotechnology and nanobiotechnology. Babolsar, Iran: Academic University (Mazandaran) publications; 2007;
  24. Medina C, Santos-Martinez MJ, Radomski A, Corrigan OI, Radomski MW. Nanoparticles: pharmacological and toxicological significance. Br J Pharmacol. 2007;150:552–558
  25. Bajpai AK, Choubey J. In vitro release dynamics of an anticancer drug from swellable gelatin nanoparticles. J Appl Polym Sci. 2006;101:2320–2332
  26. Bajpai AK, Bhanu S. Dynamics of controlled release of heparin from swellable cross-linked starch microspheres. J Mater Sci Mater Med. 2007;18:1613–1621
  27. Bajpai AK, Mishra A. Preparation and characterization of tetracycline-loaded interpenetrating polymer networks of carboxymethyl cellulose and poly(acrylic acid): water sorption and drug release study. Polym Int. 2005;54:1347–1356
  28. Bajpai AK, Saini R. Preparation and characterization of spongy cryogels of poly(vinyl alcohol)-casein system: water sorption and blood compatibility study. Polym Int. 2005;54:796–806

 No conflict of interest was reported by the authors of this article.

PII: S1549-9634(09)00259-7

doi: 10.1016/j.nano.2009.11.006

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 6, Issue 3 , Pages 453-462 , June 2010

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