Nanomedicine: Nanotechnology, Biology and Medicine
Volume 8, Issue 2 , Pages 212-220 , February 2012

In vivo tumor suppression efficacy of mesoporous silica nanoparticles-based drug-delivery system: enhanced efficacy by folate modification

  • Jie Lu, MD, PhD

      Affiliations

    • California NanoSystems Institute, Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California
  • ,
  • Zongxi Li, BS

      Affiliations

    • California NanoSystems Institute, Department of Chemistry and Biochemistry, Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California
  • ,
  • Jeffrey I. Zink, PhD

      Affiliations

    • California NanoSystems Institute, Department of Chemistry and Biochemistry, Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California
  • ,
  • Fuyuhiko Tamanoi, PhD

      Affiliations

    • California NanoSystems Institute, Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California
    • Corresponding Author InformationCorresponding author: California NanoSystems Institute, Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, 405 Hilgard Avenue, Los Angeles, CA 90095.

Received 14 April 2011 ,Accepted 3 June 2011.

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 This work was supported by the NIH grant CA133697.

 The authors report no conflict of interest.

PII: S1549-9634(11)00255-3

doi: 10.1016/j.nano.2011.06.002

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 8, Issue 2 , Pages 212-220 , February 2012