Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells

Shivani Sharma, PhD
- Department of Chemistry and Biochemistry, University of California, Los Angeles, California, USA
- California NanoSystems Institute, University of California, Los Angeles, California, USA
- Corresponding author: California Nanosystems Institute, 570 Westwood Plaza, University of California, Los Angeles, California 90095, USA.
Chintda Santiskulvong, PhD
- Department of Obstetrics and Gynecology, University of California, Los Angeles, California, USA
Laurent A. Bentolila, PhD
- Department of Chemistry and Biochemistry, University of California, Los Angeles, California, USA
- California NanoSystems Institute, University of California, Los Angeles, California, USA
JianYu Rao, MD
- Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California, USA
Oliver Dorigo, MD, PhD
- Department of Obstetrics and Gynecology, University of California, Los Angeles, California, USA
James K. Gimzewski, PhD
- Department of Chemistry and Biochemistry, University of California, Los Angeles, California, USA
- California NanoSystems Institute, University of California, Los Angeles, California, USA
- International Center for Materials Nanoarchitectonics Satellite (MANA), National Institute for Materials Science (NIMS), Tsukuba, Japan

Received 28 June 2011 ,Accepted 24 September 2011. Published online 24 October 2011 Corrected Proof

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This work was partially supported by funding from NIMS, Japan, and California Nanosystems Institute (CNSI) at UCLA. STED confocal laser scanning microscopy was performed on a Leica TCS SP5 STED confocal system at the CNSI Advanced Light Microscopy/Spectroscopy Laboratory at UCLA, supported with funding from NSF (MRI CHE-0722519).

PII: S1549-9634(11)00372-8

doi: 10.1016/j.nano.2011.09.015

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