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Improving intraperitoneal chemotherapeutic effect and preventing postsurgical adhesions simultaneously with biodegradable micelles

  • ChangYang Gong, PhD

      Affiliations

    • State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China
    • ,
  • Bing Yang, MD

      Affiliations

    • Department of Gynecology and Obstetrics, Second West China Hospital, Sichuan University, Chengdu, China
    • ,
  • ZhiYong Qian, PhD

      Affiliations

    • State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China
    • Corresponding Author InformationCorresponding author: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, China.
    • ,
  • Xia Zhao, MD

      Affiliations

    • Department of Gynecology and Obstetrics, Second West China Hospital, Sichuan University, Chengdu, China
    • ,
  • QinJie Wu, PhD

      Affiliations

    • State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China
    • ,
  • XiaoRong Qi, MD

      Affiliations

    • Department of Gynecology and Obstetrics, Second West China Hospital, Sichuan University, Chengdu, China
    • ,
  • YuJun Wang, PhD

      Affiliations

    • State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China
    • ,
  • Gang Guo, PhD

      Affiliations

    • State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China
    • ,
  • Bing Kan, PhD

      Affiliations

    • State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China
    • ,
  • Feng Luo, MD

      Affiliations

    • State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China
    • ,
  • YuQuan Wei, MD

      Affiliations

    • State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

Received 6 December 2010 ,Accepted 25 October 2011. Published online 07 December 2011 Corrected Proof

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 This work was financially supported by National 863 project (2007AA021902), Specialized Research Fund for the Doctoral Program of Higher Education (200806100065), New Century Excellent Talents in University (NCET-08-0371), Sichuan Key Technology R&D Program (2011SZ0219), and Chinese Key Basic Research Program (2010CB529906).

 Z-Y. Qian, Y-Q. Wei, X. Zhao, and C-Y. Gong designed the experiments. C-Y. Gong and B. Yang carried out experiments, analyzed the data, and wrote the manuscript. Z-Y. Qian corrected the manuscript. Q-J. Wu, X-R. Qi, and Y-J. Wang participated in the animal experiments. G. Guo participated in synthesizing the hydrogel. B. Kan and F. Luo participated in analyzing the data. All authors approved and read the final manuscript.

PII: S1549-9634(11)00516-8

doi: 10.1016/j.nano.2011.10.010

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