Nanomedicine: Nanotechnology, Biology and Medicine
Volume 8, Issue 3 , Pages 261-270 , April 2012

Nanoscale surface modification favors benign biofilm formation and impedes adherence by pathogens

  • Barbara W. Trautner, MD, PhD

      Affiliations

    • Houston VA Health Services Research and Development Center of Excellence, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    • Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    • Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
    • Corresponding Author InformationCorresponding author: Baylor College of Medicine, One Baylor Plaza, BCM 286, N1319, Houston, Texas 77030, USA.
    • ,
  • Analette I. Lopez, PhD

      Affiliations

    • Department of Chemistry, University of Houston, Houston, Texas, USA
    • ,
  • Amit Kumar, PhD

      Affiliations

    • Department of Chemistry, University of Houston, Houston, Texas, USA
    • ,
  • Danish M. Siddiq, MD

      Affiliations

    • Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    • ,
  • Kershena S. Liao, BA

      Affiliations

    • Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    • ,
  • Yan Li, PhD

      Affiliations

    • Department of Chemistry, University of Houston, Houston, Texas, USA
    • ,
  • David J. Tweardy, MD

      Affiliations

    • Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    • Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA
    • ,
  • Chengzhi Cai, PhD

      Affiliations

    • Department of Chemistry, University of Houston, Houston, Texas, USA

Received 31 January 2011 ,Accepted 29 November 2011.

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 This study was financially supported by the National Institutes of Health (NIH HD058985), Veterans’ Administration (VA RR&D B4623), a training fellowship to A.I.L. from the Keck Center Nanobiology Training Program of the Gulf Coast Consortia (NIH 5R90DK071054-03), and the Welch Foundation (E-1498).

 The laboratories of Drs. Trautner and Cai have an equal contribution to this work.

PII: S1549-9634(11)00599-5

doi: 10.1016/j.nano.2011.11.014

Nanomedicine: Nanotechnology, Biology and Medicine
Volume 8, Issue 3 , Pages 261-270 , April 2012

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