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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Gold nanoparticles: the importance of physiological principles to devise strategies for targeted drug delivery
DOI: 10.1016/j.nano.2012.01.008
Abstract: Nanotechnology and its promise for clinical translation to targeted drug delivery with limited accompanying toxicity provide exciting research opportunities that demand multidisciplinary app...
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Madhusudhan R. Papasani,
Guankui Wang,
Rodney A. Hill
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Review article
(In Press Accepted Manuscript)
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02 February 2012 |
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A Novel Therapeutic System for Malignant Glioma: Nanoformulation, Pharmacokinetic and Anti-Cancer Properties of Cell-Nano-Drug delivery
DOI: 10.1016/j.nano.2012.01.002
Abstract: Macrophage carriage, release, and anti-tumor activities of polymeric nanoformulated paclitaxel (PTX) were developed as a novel delivery system for malignant glioma. To achieve this goal, we ...
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Youhua Tao,
Miaomiao Ning,
Huanyu Dou
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Full-length article
(In Press Accepted Manuscript)
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02 February 2012 |
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Disassembly and reassembly improves morphology and thermal stability of human papillomavirus type 16 virus-like particles
DOI: 10.1016/j.nano.2012.01.007
Abstract: Recombinant human papillomavirus (HPV) 16 L1 protein self-assembles into virus-like particles (VLPs) with diameters of 40 to 60 nm, which are key components in prophylactic HPV vaccines. Mar...
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Qinjian Zhao,
Michael J. Allen,
Yang Wang,
Bei Wang,
Ning Wang,
Li Shi,
Robert D. Sitrin
et al.
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Full-length article
(In Press Accepted Manuscript)
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02 February 2012 |
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Mouse respiratory cilia with the asymmetric axonemal structure on sparsely distributed ciliary cells can generate overall directional flow
DOI: 10.1016/j.nano.2012.01.004
Abstract: Mucociliary clearance on the surface of the tracheal lumen is an important component of lung defense against dust mites and viruses. However, the axonemal structure that achieves effective c...
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Hironori Ueno,
Takuji Ishikawa,
Khanh Huy Bui,
Kohsuke Gonda,
Takashi Ishikawa,
Takami Yamaguchi
et al.
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Full-length article
(In Press Accepted Manuscript)
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02 February 2012 |
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Quantitative molecular profiling of biomarkers for pancreatic cancer with functionalized quantum dots
DOI: 10.1016/j.nano.2012.01.005
Abstract: Applications in nanomedicine, such as diagnostics and targeted therapeutics, rely on the detection and targeting of membrane biomarkers. In this paper we demonstrate absolute quantitative pr...
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Kwan Hyi Lee,
Justin F. Galloway,
Jeaho Park,
Charlene M. Dvoracek,
Matthew Dallas,
Konstaninos Konstantopoulos,
Anirban Maitra,
Peter C. Searson
et al.
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Full-length article
(In Press Accepted Manuscript)
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02 February 2012 |
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Gene delivery nanoparticles specific for human microvasculature and macrovasculature
DOI: 10.1016/j.nano.2012.01.006
Abstract: Endothelial cell dysfunction is a critical component of ocular diseases such as age-related macular degeneration and diabetic retinopathy. An important limitation in endothelial cell researc...
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Ron B. Shmueli,
Joel C. Sunshine,
Zhenhua Xu,
Elia J. Duh,
Jordan J. Green
et al.
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Full-length article
(In Press Accepted Manuscript)
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02 February 2012 |
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Peptide PHSCNK as an integrin α5β1 antagonist targets stealth liposomes to integrin-overexpressing melanoma
DOI: 10.1016/j.nano.2012.01.003
Abstract: As an integrin α5β1 antagonist, N-acetyl-proline-histidine-serine-cysteine-asparagine-amide (Ac-PHSCN-NH2) is currently in phase II trials for various cancer therapies. In the present work, ...
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Wenbing Dai,
Tingyuan Yang,
Yiguang Wang,
Xueqing Wang,
Jiancheng Wang,
Xuan Zhang,
Qiang Zhang
et al.
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Full-length article
(In Press Accepted Manuscript)
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02 February 2012 |
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Initial studies of mechanical compression on neurogenesis with neonatal neural stem cells
DOI: 10.1016/j.nano.2012.01.001
Abstract: In this article we demonstrate the effect of mechanical compression on the behavior of cultured neural stem cells using a microelectromechanical system platform. Polydimethylsiloxane (PDMS)-...
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Leyla Esfandiari,
Michelle Paff,
William C. Tang
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Short communication
(In Press Uncorrected Proof)
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27 January 2012 |
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Harnessing nanoparticles to improve toxicity after head and neck radiation
DOI: 10.1016/j.nano.2011.12.011
Abstract: This article reports the evaluation of cerium oxide (CeO2) nanoparticles' ability to decrease xerostomia and radiation-induced dermatitis in mice after head and neck radiation. Mice were irr...
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Rafael A. Madero-Visbal,
Beatrice E. Alvarado,
Jimmie F. Colon,
Cheryl H. Baker,
Melissa S. Wason,
Beth Isley,
Sudipta Seal,
Chris M. Lee,
Soumen Das,
Rafael Mañon
et al.
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Full-length article
(In Press Uncorrected Proof)
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16 January 2012 |
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pH-Dependent nanostructure based on isoquinoline-cyclodextrin conjugate for thrombosis therapy
DOI: 10.1016/j.nano.2011.12.008
Abstract: The modification of 3S-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (THIQA) with β-cyclodextrin (β-CD) provides an oral antithrombotic agent, 6-(3′S-isoquinoline-3′-carboxylaminoethylami...
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Li Li,
Ming Zhao,
Wenhao Li,
Yuji Wang,
Chunna Liu,
Zhuge Zhang,
Songchun Su,
Shiqi Peng
et al.
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Full-length article
(In Press Uncorrected Proof)
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16 January 2012 |
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Improving interstitial transport of macromolecules through reduction in cell volume fraction in tumor tissues
DOI: 10.1016/j.nano.2011.12.009
Abstract: Interstitial transport of large molecules and nanoparticles is an important concern in nanomedicine-mediated cancer treatment. To that end, the study was proposed to improve the transport th...
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Sarah McGuire,
Fan Yuan
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Full-length article
(In Press Uncorrected Proof)
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16 January 2012 |
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Electrostatic assembly of a DNA superparamagnetic nano-tool for simultaneous intracellular delivery and in situ monitoring
DOI: 10.1016/j.nano.2011.12.010
Abstract: A superparamagnetic γFe2O3 nanocarrier was developed, characterized by spectroscopic methods and evaluated for the delivery of a decoy oligonucleotide (dODN) in human colon carcinoma SW 480 ...
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Frédéric Geinguenaud,
Inès Souissi,
Remi Fagard,
Laurence Motte,
Yoann Lalatonne
et al.
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Full-length article
(In Press Uncorrected Proof)
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16 January 2012 |
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Preclinical evaluation of a pulmonary delivered paclitaxel-loaded lipid nanocarrier antitumor effect
DOI: 10.1016/j.nano.2011.12.007
Abstract: Lung cancer remains a leading cause of death due to the low efficacy of chemotherapy, mainly related to the administration route used. Therefore, alternative administration routes are needed...
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Mafalda Videira,
António J. Almeida,
Àngels Fabra
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Full-length article
(In Press Corrected Proof)
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29 December 2011 |
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Activation of TrkB receptors by NGFβ mimetic peptide conjugated polymersome nanoparticles
DOI: 10.1016/j.nano.2011.12.005
Abstract: Activation of tyrosine kinase receptor B (TrkB), a neurotrophin receptor, has been shown to increase neuronal cell survival and promote regeneration. Stimulation of the TrkB receptor by neur...
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Roy Soumen,
A.H. Johnston,
Syed Tarique Moin,
Jozsef Dudas,
T.A. Newman,
Barbara Hausott,
Anneliese Schrott-Fischer,
Rudolf Glueckert
et al.
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Short communication
(In Press Corrected Proof)
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28 December 2011 |
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Albumin coupled lipid nanoemulsions of diclofenac for targeted delivery to inflammation
DOI: 10.1016/j.nano.2011.12.006
Abstract: Diclofenac lipid nanoemulsions (DLNEs) were prepared with different compositions. Based on size, PDI, zeta potential, and in vitro drug release, the optimized DLNEs (DLNE-4 and DLNE-7) were ...
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Kandadi Prabhakar,
Syed Muzammil Afzal,
Goparaboina Surendar,
Veerabrahma Kishan
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Full-length article
(In Press Uncorrected Proof)
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28 December 2011 |
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ERα signaling imparts chemotherapeutic selectivity to selenium nanoparticles in breast cancer
DOI: 10.1016/j.nano.2011.12.003
Abstract: The present study focuses on the synthesis of stable selenium nanoparticles (SeNPs) and the elucidation of their mechanism of action in preventing the growth of mammary tumors. Selenious aci...
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Kiritkumar K. Vekariya,
Jasmine Kaur,
Kulbhushan Tikoo
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells
DOI: 10.1016/j.nano.2011.12.004
Abstract: Peptides featuring the LR(S/T) motif were identified that could specifically bind to the C-type lectin-like molecule-1 (CLL1), a protein preferentially expressed on acute myeloid leukemia st...
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Hongyong Zhang,
Juntao Luo,
Yuanpei Li,
Paul T. Henderson,
Yanchun Wang,
Sebastian Wachsmann-Hogiu,
Weixin Zhao,
Kit S. Lam,
Chong-xian Pan
et al.
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Nanostructured silver vanadate as a promising antibacterial additive to water-based paints
DOI: 10.1016/j.nano.2011.11.012
Abstract: In this article, we report the use of nanostructured silver vanadate as a promising antibacterial additive to water-based paints that has potential for applications in bathrooms, kitchens, a...
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Raphael D. Holtz,
Bruna A. Lima,
Antônio G. Souza Filho,
Marcelo Brocchi,
Oswaldo L. Alves
et al.
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Nanoscale surface modification favors benign biofilm formation and impedes adherence by pathogens
DOI: 10.1016/j.nano.2011.11.014
Abstract: We have found in vitro that a biofilm of benign Escherichia coli 83972 interferes with urinary catheter colonization by pathogens, and in human studies E. coli 83972–coated urinary catheters...
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Barbara W. Trautner,
Analette I. Lopez,
Amit Kumar,
Danish M. Siddiq,
Kershena S. Liao,
Yan Li,
David J. Tweardy,
Chengzhi Cai
et al.
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Mono-dispersed high magnetic resonance sensitive magnetite nanocluster probe for detection of nascent tumors by magnetic resonance molecular imaging
DOI: 10.1016/j.nano.2011.11.013
Abstract: Sensitive molecular imaging and detection of tumors or their supporting neovascularity require high-avidity, target-specific probes, which produce robust signal amplification compatible with...
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Chunfu Zhang,
Xuan Xie,
Sheng Liang,
Mingli Li,
Yajie Liu,
Hongchen Gu
et al.
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Polystyrene nanoparticles affecting blood coagulation
DOI: 10.1016/j.nano.2011.12.001
Abstract: The association of nanoparticles (NPs) with blood coagulation proteins may influence the natural balance between pro- and anticoagulant pathways. We investigated whether polystyrene NPs, whe...
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Cecilia Oslakovic,
Tommy Cedervall,
Sara Linse,
Björn Dahlbäck
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Quantitative characterization of the lipid encapsulation of quantum dots for biomedical applications
DOI: 10.1016/j.nano.2011.12.002
Abstract: The water solubilization of nanoparticles is key for many applications in biomedicine. Despite the importance of surface functionalization, progress has been largely empirical and very few s...
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Justin F. Galloway,
Alan Winter,
Kwan Hyi Lee,
Jea Ho Park,
Charlene Dvoracek,
Peter Devreotes,
Peter C. Searson
et al.
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Improving intraperitoneal chemotherapeutic effect and preventing postsurgical adhesions simultaneously with biodegradable micelles
DOI: 10.1016/j.nano.2011.10.010
Abstract: The two major concerns after cytoreductive surgery of abdominal and pelvic malignancies are residual tumors and peritoneal adhesions, which are inevitable and have great impact on prognosis....
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ChangYang Gong,
Bing Yang,
ZhiYong Qian,
Xia Zhao,
QinJie Wu,
XiaoRong Qi,
YuJun Wang,
Gang Guo,
Bing Kan,
Feng Luo,
YuQuan Wei
et al.
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Full-length article
(In Press Corrected Proof)
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07 December 2011 |
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In vitro mechanistic study of cell death and in vivo performance evaluation of RGD grafted PEGylated docetaxel liposomes in breast cancer
DOI: 10.1016/j.nano.2011.11.008
Abstract: Objectives of the investigations were to prepare RGD grafted docetaxel liposomes (RGD-PEG-LP-DC) using supercritical fluid technology and evaluate it in vitro for cytotoxicity, DNA content a...
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Sachin Naik,
Deepa Patel,
Krishna Chuttani,
Anil K. Mishra,
Ambikanandan Misra
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Nanoresonator chip-based RNA sensor strategy for detection of circulating tumor cells: response using PCA3 as a prostate cancer marker
DOI: 10.1016/j.nano.2011.11.009
Abstract: There is widespread interest in circulating tumor cells (CTCs) in blood. Direct detection of CTCs (often < 1/mL) is complicated by a number of factors, but the presence of ∼103 to 104 cop...
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James A. Sioss,
Rustom Bhiladvala,
Weihua Pan,
Mingwei Li,
Susan Patrick,
Ping Xin,
Stacey L. Dean,
Christine D. Keating,
Theresa S. Mayer,
Gary A. Clawson
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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In vitro study of magnetite-amyloid β complex formation
DOI: 10.1016/j.nano.2011.11.010
Abstract: Biogenic magnetite (Fe3O4) has been identified in human brain tissue. However, abnormal concentration of magnetite nanoparticles in the brain has been observed in different neurodegenerative...
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Mònica Mir,
Islam Bogachan Tahirbegi,
Juan José Valle-Delgado,
Xavier Fernàndez-Busquets,
Josep Samitier
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Multifunctional nanoplatforms for fluorescence imaging and photodynamic therapy developed by post-loading photosensitizer and fluorophore to polyacrylamide nanoparticles
DOI: 10.1016/j.nano.2011.11.011
Abstract: We report a novel post-loading approach for constructing a multifunctional biodegradable polyacrylamide (PAA) nanoplatform for tumor-imaging (fluorescence) and photodynamic therapy (PDT). Th...
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Anurag Gupta,
Shouyan Wang,
Paula Pera,
K.V.R. Rao,
Nayan Patel,
Tymish Y. Ohulchanskyy,
Joseph Missert,
Janet Morgan,
Yong-Eun Koo-Lee,
Raoul Kopelman,
Ravindra K. Pandey
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Release profile and transscleral permeation of triamcinolone acetonide loaded nanostructured lipid carriers (TA-NLC): in vitro and ex vivo studies
DOI: 10.1016/j.nano.2011.10.015
Abstract: Nanostructured lipid carriers (NLC) have been developed for sustained release of triamcinolone acetonide (TA), a corticosteroid commonly indicated for macular edema, neovascularization, and ...
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Joana Araújo,
Maria L. Garcia,
Mireia Mallandrich,
Eliana B. Souto,
Ana C. Calpena
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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An investigation on the antibacterial, cytotoxic, and antibiofilm efficacy of starch-stabilized silver nanoparticles
DOI: 10.1016/j.nano.2011.11.007
Abstract: The increased emergence of drug resistant microbes creates a major challenge to the scientific community for successful development of effective therapeutics. The antimicrobial activities of...
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Soumitra Mohanty,
Saswati Mishra,
Prajna Jena,
Biju Jacob,
Biplab Sarkar,
Avinash Sonawane
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Paclitaxel-loaded polymeric micelles based on poly(ɛ-caprolactone)-poly(ethylene glycol)-poly(ɛ-caprolactone) triblock copolymers: in vitro and in vivo evaluation
DOI: 10.1016/j.nano.2011.11.005
Abstract: The purpose of this study was to develop polymeric nanoscale drug-delivery system (nano-DDS) for paclitaxel (PTX) from poly(ɛ-caprolactone)-poly(ethylene glycol)-poly(ɛ-caprolactone) (PCL-PE...
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Linhua Zhang,
Yingna He,
Guilei Ma,
Cunxian Song,
Hongfan Sun
et al.
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Full-length article
(In Press Corrected Proof)
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18 November 2011 |
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Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation
DOI: 10.1016/j.nano.2011.11.004
Abstract: Because of their outstanding physical properties, carbon nanotubes (CNTs) are promising new materials in the field of nanotechnology. It is therefore imperative to assess their adverse effec...
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Etienne Meunier,
Agnès Coste,
David Olagnier,
Hélène Authier,
Lise Lefèvre,
Christophe Dardenne,
José Bernad,
Maryse Béraud,
Emmanuel Flahaut,
Bernard Pipy
et al.
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Full-length article
(In Press Corrected Proof)
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17 November 2011 |
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Photothermal release of small molecules from gold nanoparticles in live cells
DOI: 10.1016/j.nano.2011.10.012
Abstract: The ability of gold (Au) nanoparticles (NPs) to generate heat efficiently by absorbing visible and near-infrared (NIR) light holds great promise as a means to trigger chemical and biochemica...
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Wesley F. Zandberg,
Amir Bahman Samsam Bakhtiari,
Zach Erno,
Dennis Hsiao,
Byron D. Gates,
Thomas Claydon,
Neil R. Branda
et al.
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Full-length article
(In Press Corrected Proof)
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17 November 2011 |
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Self-Assembly and liver targeting of sulfated chitosan nanoparticles functionalized with glycyrrhetinic acid
DOI: 10.1016/j.nano.2011.11.002
Abstract: A drug carrier based on glycyrrhetinic acid-modified sulfated chitosan (GA-SCTS) was synthesized. The glycyrrhetinic acid (GA) acted as both a hydrophobic group and a liver-targeting ligand....
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Qin Tian,
Xiu-Hua Wang,
Wei Wang,
Chuang-Nian Zhang,
Ping Wang,
Zhi Yuan
et al.
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Full-length article
(In Press Corrected Proof)
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17 November 2011 |
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Development and evaluation of a dual-modality (MRI/SPECT) molecular imaging bioprobe
DOI: 10.1016/j.nano.2011.10.013
Abstract: Specific bioprobes for single photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI) have enormous potential for use in cancer imaging in near-future clinical setti...
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Ripen Misri,
Dominik Meier,
Andrew C. Yung,
Piotr Kozlowski,
Urs O. Häfeli
et al.
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Full-length article
(In Press Corrected Proof)
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17 November 2011 |
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Lapatinib/Paclitaxel polyelectrolyte nanocapsules for overcoming multidrug resistance in ovarian cancer
DOI: 10.1016/j.nano.2011.10.014
Abstract: The sonication-assisted layer-by-layer (SLBL) technology was developed to combine necessary factors for an efficient drug-delivery system: (i) control of nanocolloid size within 100 – 300 nm...
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Daniele Vergara,
Claudia Bellomo,
Xingcai Zhang,
Viviana Vergaro,
Andrea Tinelli,
Vito Lorusso,
Ross Rinaldi,
Yuri M. Lvov,
Stefano Leporatti,
Michele Maffia
et al.
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Full-length article
(In Press Corrected Proof)
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17 November 2011 |
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Bioactive silica-based nanoparticles stimulate bone-forming osteoblasts, suppress bone-resorbing osteoclasts, and enhance bone mineral density in vivo
DOI: 10.1016/j.nano.2011.11.003
Abstract: Bone is a dynamic tissue that undergoes renewal throughout life in a process whereby osteoclasts resorb worn bone and osteoblasts synthesize new bone. Imbalances in bone turnover lead to bon...
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George R. Beck,
Shin-Woo Ha,
Corinne E. Camalier,
Masayoshi Yamaguchi,
Yan Li,
Jin-Kyu Lee,
M. Neale Weitzmann
et al.
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Full-length article
(In Press Corrected Proof)
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17 November 2011 |
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Novel micelles based on amphiphilic branched PEG as carriers for fenretinide
DOI: 10.1016/j.nano.2011.10.008
Abstract: This study reports on the preparation and evaluation of amphiphilic macromolecules based on branched polyethylene glycol covalently linked with alkyl hydrocarbon chains. These macromolecules...
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Isabella Orienti,
Guendalina Zuccari,
Mirella Falconi,
Gabriella Teti,
Nicola A. Illingworth,
Gareth J. Veal
et al.
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Full-length article
(In Press Corrected Proof)
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16 November 2011 |
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Cancer cell response to nanoparticles: criticality and optimality
DOI: 10.1016/j.nano.2011.10.009
Abstract: A stochastic variation in size and electrical parameters is common in nanoparticles. Synthesizing gold nanoparticles with a varying range of size and zeta potential, we show that there is cl...
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Hirak Kumar Patra,
Anjan Kr Dasgupta
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Full-length article
(In Press Corrected Proof)
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16 November 2011 |
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New strategy of efficient inhibition of cancer cells by carborane carboxylic acid–CdTe nanocomposites
DOI: 10.1016/j.nano.2011.10.011
Abstract: Nanoconjugates composed of drug molecules encapsulated in quantum dots (QDs) attract enormous attention due to their promising bioimaging and biomedical applications. Here, the anticancer ef...
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Chunhui Wu,
Lixin Shi,
Qingning Li,
Hui Jiang,
Matthias Selke,
Hong Yan,
Xuemei Wang
et al.
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Full-length article
(In Press Corrected Proof)
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16 November 2011 |
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Gold-peptide nanoconjugate cellular uptake is modulated by serum proteins
DOI: 10.1016/j.nano.2011.10.007
Abstract: Gold nanoparticles (AuNPs, 20 nm) were conjugated with two different cysteine-terminated peptides. Radio-ligand binding studies were conducted to characterize AuNP-peptide binding, suggestin...
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Guankui Wang,
Madhusudhan R. Papasani,
Pallavi Cheguru,
Patrick J. Hrdlicka,
Rodney A. Hill
et al.
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Full-length article
(In Press Corrected Proof)
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02 November 2011 |
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Preclinical study of the cyclodextrin-polymer conjugate of camptothecin CRLX101 for the treatment of gastric cancer
DOI: 10.1016/j.nano.2011.09.007
Abstract: Camptothecin showed remarkable anticancer activity in animal models of cancer but was restricted in clinical use for its adverse toxicity in patients. The preclinical efficacy of CRLX101, a ...
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Shikha Gaur,
Linling Chen,
Terence Yen,
Yafan Wang,
Bingsen Zhou,
Mark Davis,
Yun Yen
et al.
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Full-length article
(In Press Corrected Proof)
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26 October 2011 |
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Classification of lung cancer histology by gold nanoparticle sensors
DOI: 10.1016/j.nano.2011.10.001
Abstract: We propose a nanomedical device for the classification of lung cancer (LC) histology. The device profiles volatile organic compounds (VOCs) in the headspace of (subtypes of) LC cells, using ...
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Orna Barash,
Nir Peled,
Ulrike Tisch,
Paul A. Bunn,
Fred R. Hirsch,
Hossam Haick
et al.
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Full-length article
(In Press Corrected Proof)
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26 October 2011 |
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In vitro study of ethosome penetration in human skin and hypertrophic scar tissue
DOI: 10.1016/j.nano.2011.10.006
Abstract: The purpose of this study is to characterize a novel transdermal delivery carrier, ethosomes containing 5-fluorouracil. The delivery of drugs from ethosomes in human hypertrophic scar (HS) a...
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Zhen Zhang,
Yan Wo,
Yixin Zhang,
Danru Wang,
Rong He,
Huijin Chen,
Daxiang Cui
et al.
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Full-length article
(In Press Corrected Proof)
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26 October 2011 |
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Cytotoxicity of functionalized carbon nanotubes in J774A macrophages
DOI: 10.1016/j.nano.2011.10.002
Abstract: Cytotoxicity of carbon nanotubes (CNTs) is a prime concern for its use as antigen carriers. Here we evaluated the cytotoxic effect of unpurified (UP-CNTs), purified (P-CNTs), fluorescein iso...
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Silvia Lorena Montes-Fonseca,
Erasmo Orrantia-Borunda,
Alfredo Aguilar-Elguezabal,
Carmen González Horta,
Patricia Talamás-Rohana,
Blanca Sánchez-Ramírez
et al.
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Full-length article
(In Press Corrected Proof)
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26 October 2011 |
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Synergistic effects of cell-penetrating peptide Tat and fusogenic peptide HA2-enhanced cellular internalization and gene transduction of organosilica nanoparticles
DOI: 10.1016/j.nano.2011.10.003
Abstract: The nonviral gene delivery system is an attractive alternative to cancer therapy. A new kind of gelatin-silica nanoparticles (GSNPs) was developed through a two-step sol–gel procedure. To im...
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She-fang Ye,
Miao-miao Tian,
Tian-xiao Wang,
Lei Ren,
Dong Wang,
Li-hua Shen,
Ting Shang
et al.
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Full-length article
(In Press Corrected Proof)
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26 October 2011 |
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Enhancement of focused ultrasound with microbubbles on the treatments of anticancer nanodrug in mouse tumors
DOI: 10.1016/j.nano.2011.10.005
Abstract: Ultrasound sonication with microbubbles (MBs) has the potential to enhance the delivery of nanoparticles into the sonicated tumors. In this study, we investigated the feasibility of focused ...
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Chung-Yin Lin,
Jia-Rong Li,
Hsiao-Ching Tseng,
Ming-Fang Wu,
Win-Li Lin
et al.
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Full-length article
(In Press Corrected Proof)
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26 October 2011 |
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Visible light–responsive core-shell structured In2O3@CaIn2O4 photocatalyst with superior bactericidal properties and biocompatibility
DOI: 10.1016/j.nano.2011.09.016
Abstract: Antibacterial activity of photocatalytic substrates is primarily induced by ultraviolet light irradiation. Visible light–responsive photocatalysts were recently discovered, offering greater ...
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Wen-Ku Chang,
Der-Shan Sun,
Hao Chan,
Pai-Tsang Huang,
Wen-Shiang Wu,
Ching-Hui Lin,
Yao-Hsuan Tseng,
Yi-Hung Cheng,
Chun-Chieh Tseng,
Hsin-Hou Chang
et al.
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Full-length article
(In Press Corrected Proof)
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26 October 2011 |
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EGFR-mediated intracellular delivery of Pc 4 nanoformulation for targeted photodynamic therapy of cancer: in vitro studies
DOI: 10.1016/j.nano.2011.09.012
Abstract: In photodynamic therapy (PDT), the light activation of a photosensitizer leads to the generation of reactive oxygen species that can trigger various mechanisms of cell death. Harnessing this...
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Alyssa M. Master,
Yizhi Qi,
Nancy L. Oleinick,
Anirban Sen Gupta
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Full-length article
(In Press Corrected Proof)
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24 October 2011 |
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Diagnostic applications of Raman spectroscopy
DOI: 10.1016/j.nano.2011.09.013
Abstract: Raman spectroscopy has been widely used in various fields of science. It has been successfully utilized to qualitatively and quantitatively determine the molecular compositions of solid, liq...
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Qiang Tu,
Chang Chang
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Review article
(In Press Corrected Proof)
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24 October 2011 |
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Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells
DOI: 10.1016/j.nano.2011.09.015
Abstract: The exact molecular mechanisms of ovarian cancer platinum resistance are not well understood, and biomarkers to reliably predict ovarian cancer resistance to platinum and other chemotherapeu...
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Shivani Sharma,
Chintda Santiskulvong,
Laurent A. Bentolila,
JianYu Rao,
Oliver Dorigo,
James K. Gimzewski
et al.
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Full-length article
(In Press Corrected Proof)
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24 October 2011 |
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Development of a method for magnetic labeling of platelets
DOI: 10.1016/j.nano.2011.09.008
Abstract: Platelets play a dominant role in the pathogenesis of bleeding disorders and cardiovascular pathology (e.g., myocardial infarction). Nonradioactive labeling of platelets may offer several cl...
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Konstanze Aurich,
Mark-Christopher Spoerl,
Birgitt Fürll,
Rabea Sietmann,
Andreas Greinacher,
Norbert Hosten,
Werner Weitschies
et al.
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Full-length article
(In Press Corrected Proof)
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24 October 2011 |
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Induction of tumor-specific immunity by multi-epitope rat HER2/neu-derived peptides encapsulated in LPD Nanoparticles
DOI: 10.1016/j.nano.2011.09.010
Abstract: The goal of study was first to design multi-epitope peptides from the rat HER2/neu (rHER2/neu) oncogene and then to evaluate the effectiveness of these peptides encapsulated in liposome-poly...
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Seyed Amir Jalali,
Mojtaba Sankian,
Jalil Tavakkol-Afshari,
Mahmoud Reza Jaafari
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Full-length article
(In Press Corrected Proof)
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24 October 2011 |
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Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles
DOI: 10.1016/j.nano.2011.09.006
Abstract: Nanosized cell-derived membrane vesicles are increasingly recognized as therapeutic vehicles and high-potential biomarkers for several diseases. Currently available methods allow bulk analys...
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Esther N.M. Nolte-'t Hoen,
Els J. van der Vlist,
Marian Aalberts,
Hendrik C.H. Mertens,
Berend Jan Bosch,
Willem Bartelink,
Enrico Mastrobattista,
Ethlinn V.B. van Gaal,
Willem Stoorvogel,
Ger J.A. Arkesteijn,
Marca H.M. Wauben
et al.
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Full-length article
(In Press Corrected Proof)
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24 October 2011 |
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A new method for tumor detection using induced acoustic waves from tagged magnetic nanoparticles
DOI: 10.1016/j.nano.2011.09.011
Abstract: Magnetoacoustic detection is a new method for the noninvasive, early detection of cancer. It uses specific superparamagnetic nanoparticles (NPs) that bind to tumor sites together with magnet...
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Idan Steinberg,
Moshe Ben-David,
Israel Gannot
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Full-length article
(In Press Corrected Proof)
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24 October 2011 |
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Factorial analysis of adaptable properties of self-assembling peptide matrix on cellular proliferation and neuronal differentiation of pluripotent embryonic carcinoma
DOI: 10.1016/j.nano.2011.09.001
Abstract: An integrative and quantitative approach for systematically studying the effects of changing the matrix environment on pluripotent cell viability and neuronal differentiation was demonstrate...
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Qianqian Li,
Wai Hung Cheung,
King L. Chow,
Rutledge G. Ellis-Behnke,
Ying Chau
et al.
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Full-length article
(In Press Corrected Proof)
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22 September 2011 |
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Improved antibacterial and antibiofilm activity of magnesium fluoride nanoparticles obtained by water-based ultrasound chemistry
DOI: 10.1016/j.nano.2011.09.002
Abstract: Antibiotic resistance has prompted the search for new agents that can inhibit bacterial growth. We recently reported on the antimicrobial and antibiofilm activities of nanosized magnesium fl...
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Jonathan Lellouche,
Alexandra Friedman,
Jean-Paul Lellouche,
Aharon Gedanken,
Ehud Banin
et al.
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Full-length article
(In Press Corrected Proof)
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22 September 2011 |
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Antiangiogenic effect of silicate nanoparticle on retinal neovascularization induced by vascular endothelial growth factor
DOI: 10.1016/j.nano.2011.09.003
Abstract: Angiogenesis-related blindness indicates the spectrum of retinal diseases that are caused by pathological angiogenesis, resulting in catastrophic vision loss. We aimed to demonstrate the ant...
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Dong Hyun Jo,
Jin Hyoung Kim,
Young Suk Yu,
Tae Geol Lee,
Jeong Hun Kim
et al.
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Full-length article
(In Press Corrected Proof)
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22 September 2011 |
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Magnetic-plasmonic nanoparticles for the life sciences: calculated optical properties of hybrid structures
DOI: 10.1016/j.nano.2011.09.004
Abstract: Magnetic-plasmonic nanoparticles, combining magnetic and plasmonic components, are promising structures for use in life sciences. Optical properties of core-shell magnetite-gold nanostructur...
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Ward Brullot,
Ventsislav K. Valev,
Thierry Verbiest
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Full-length article
(In Press Corrected Proof)
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22 September 2011 |
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Solid lipid nanoparticles loading candesartan cilexetil enhance oral bioavailability: in vitro characteristics and absorption mechanism in rats
DOI: 10.1016/j.nano.2011.08.016
Abstract: Candesartan cilexetil (CC) is widely used for the treatment of hypertension and heart failure, but it shows very poor aqueous solubility and very low oral absorption. In this work, CC-loaded...
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Zhiwen Zhang,
Fang Gao,
Huihui Bu,
Jisheng Xiao,
Yaping Li
et al.
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Full-length article
(In Press Corrected Proof)
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19 September 2011 |
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Iron oxide nanoparticles for targeted cancer imaging and diagnostics
DOI: 10.1016/j.nano.2011.08.017
Abstract: Superparamagnetic iron oxide nanoparticles (SPIONs) have proven to be highly effective contrast agents for the magnetic resonance imaging diagnosis of solid tumors. This review examines the ...
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Joshua E. Rosen,
Lorena Chan,
Dar-Bin Shieh,
Frank X. Gu
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Review article
(In Press Corrected Proof)
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19 September 2011 |